一、基本情况

职称：副研究员

单位：海南大学南繁学院/崖州湾国家实验室

邮箱：yuanhonglun@hotmail.com

研究领域：代谢组学方法开发与应用

教育背景：

2008.09-2012.07：山东农业大学，理学学士学位

2012.09-2019.07：华中农业大学，理学博士学位

工作简历：

2019.07-2025.12：海南大学，热带农林学院，副教授

2026.01-至今：海南大学，南繁学院，副研究员

二、科研概况

研究方向:

开发质谱采集新模式，并使用Python语言开发基于传统算法和深度学习模型的代谢组学新方法，拟在提升基于LC–MS与GC–MS代谢组方法的灵敏度、覆盖度、准确性与易用性。基于所建方法解析作物营养、风味与胁迫应答相关代谢物组成及其合成调控，为代谢性状育种提供数据与方法支撑。相关方法亦已拓展至医学代谢组领域。

代表性成果：（#Co-first author, *Corresponding author, 下划线为课题组学生）

1. Yuan Honglun#; Cao Guangping#; Hou Xiaodong#; Huang Menglan#; Du Pengmeng#; Tan Tingting; Zhang Youjin; Zhou Haihong; Liu Xianqing; Liu Ling; Jiangfang Yiding; Li Yufei; Liu Zhenhuan; Fang Chuanying; Zhao Liqing; Fernie Alisdair R.; Luo Jie*; Development of a widely targeted volatilomics method for profiling volatilomes in plants, Mol Plant, 2022, 15(1): 189-202. (SCI, 1区, IF (2022) = 27.5, 高被引论文)

2. Yuan Honglun#; Jiangfang Yiding#; Liu Zhenhuan#; Su Rongxiu#; Li Qiao; Fang Chuanying; Huang Sishu; Liu Xianqing; Fernie Alisdair; Luo Jie*; WTV2.0: A high-coverage plant volatilomics method with a comprehensive selective ion monitoring acquisition mode, Mol Plant, 2024, 17(6): 972-985. (SCI, 1区, IF (2024) = 24.1, 高被引论文，热点论文)

3. Li Yan#; Miao Yuanyuan#; Yuan Honglun#; Huang Fengkun; Sun Mingqi; He Liqiang; Liu Xianqing; Luo Jie*; Volatilome-based GWAS identifies OsWRKY19 and OsNAC021 as key regulators of rice aroma, Mol Plant, 2024, 17(12): 1866-1882. (SCI, 1区, IF (2024) = 24.1)

4. Huang Sishu#; Li Xindong#; An Kejin; Xu Congping; Liu Zhenhuan; Wang Guan; Hou Huanteng; Zhang Ran; Wang Yutong; Yuan Honglun*; Luo Jie*; Metabolomic analysis reveals the diversity of defense metabolites in nine cereal crops, Plants, 2025, 14(4) (SCI, 2区, IF (2025) = 4.1)

5. Li Qiao; Li Shaofang; Luo Jie*; Yuan Honglun*; Predictive models of odor contribution and thresholds for volatiles in identification of novel crop aroma compounds, Metabolites, 2025, 15(11) (SCI, 3区, IF(2025) = 3.7)

6. Du Pengmeng#; Yuan Honglun#; Chen Yayu; Zhou Haihong; Zhang Youjin; Huang Menglan; Jiangfang Yiding; Su Rongxiu; Chen Qiyu; Lai Jun; Guan Lingliang; Ding Yuanhao; Hu Haiyan*; Luo Jie*; Identification of key aromatic compounds in basil (Ocimum L.) using sensory evaluation, metabolomics and volatilomics analysis, Metabolites, 2023, 13(1) (SCI, 3区, IF (2023) = 3.5)

7. Zhang Youjin#; Su Rongxiu#; Yuan Honglun; Zhou Haihong; Jiangfang Yiding; Liu Xianqing; Luo Jie*; Widely targeted volatilomics and metabolomics analysis reveal the metabolic composition and diversity of Zingiberaceae plants, Metabolites, 2023, 13(6) (SCI, 3区, IF (2023) = 3.5)

8. Liu Zhenhuan#; Wang Yutong#; Xu Hang#; Zhu Jinjin#; Zhai Hongxu; Zhu Shurui; Wang Qiming; Yuan Honglun; Du Pengmeng; Zhou Junjie; Liu Xianqing; Xu Congping; Yang Zhuang*; Luo Jie*; Integrative analyses of metabolome and transcriptome reveal the regulatory network underlying flavor differences in lychee pulp from different varieties, Plant Physiol Bioch, 2025, 229: 110594. (SCI, 2区, IF (2025) = 5.7)

9. Zhou Junjie; Liu Chengyuan; Chen Qiyu; Liu Ling; Niu Shuying; Chen Ridong; Li Kang; Sun Yangyang; Shi Yuheng; Yang Chenkun; Shen Shuangqian; Li Yufei; Xing Junwei; Yuan Honglun; Liu Xianqing; Fang Chuanying; Fernie Alisdair R.; Luo Jie*; Integration of rhythmic metabolome and transcriptome provides insights into the transmission of rhythmic fluctuations and temporal diversity of metabolism in rice, Science China-Life Sciences, 2022, 65(9): 1794-1810. (SCI, 1区, IF (2022) = 10.4)

10. Yuan Honglun; Xu Yong; Chen Yaozhong; Zhan Yangyang; Wei Xuetuan; Li Lu; Wang Dong; He Penghui; Li Shengqing; Chen Shouwen*; Metabolomics analysis reveals global acetoin stress response of Bacillus licheniformis, Metabolomics, 2019, 15(3): 25. (SCI, 3区, IF (2019) = 2.9)

科研项目:

1. 国家自然科学基金地区科学基金项目，32560113，新一代高定性覆盖度广泛靶向挥发组学方法的开发及其在水稻香味物质合成调控机制解析中的应用，2026-01-01至2029-12-31，在研，主持；

2. 海南省自然科学基金面上项目，320MS011，基于广泛靶向代谢组的挥发性萜类检测新方法及在胡椒挥发性萜类研究中的应用，2020-12-26至2023-12-25，已结题，主持；

3. 海南大学科研启动基金，基于气质联用的新一代广泛靶向植物挥发组学方法研究，2022/11至2027/11，在研，主持。

其他：

受邀于2024年第一届多维组学昆仑论坛，2024年第五届植物代谢国际会议以及2025年第三届全国植物代谢生物学大会宣讲所开发方法及应用。所开发技术体系已与国内外代谢组检测及质谱公司合作，实现标准化部署，形成落地的商业化代谢组学解决方案。